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Folipastatin

Names

[ CAS No. ]:
139959-71-0

[ Name ]:
Folipastatin

[Synonym ]:
11H-Dibenzo(b,e)(1,4)dioxepin-11-one,3,8-dihydroxy-4,9-dimethyl-1,6-bis(1-methyl-1-propenyl)-,(Z,Z)
folipastatin
11H-Dibenzo(b,e)(1,4)dioxepin-11-one,1,6-bis(1-methyl-1-propenyl)-3,8-dihydroxy-4,9-dimethyl-,(Z,Z)

Biological Activity

[Description]:

Folipastatin is a potent inhibitor of phospholipase A2 with an IC50 of 39 μM. Folipastatin is a new depsidone compound from Aspergillus unguis[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[Target]

phospholipase A2[1]


[References]

[1]. Hamano K, et al. Folipastatin, a new depsidone compound from Aspergillus unguis as an inhibitor of phospholipase A2. Taxonomy, fermentation, isolation, structure determination and biological properties.

Chemical & Physical Properties

[ Density]:
1.213g/cm3

[ Boiling Point ]:
588.3ºC at 760mmHg

[ Molecular Formula ]:
C23H24O5

[ Molecular Weight ]:
380.43400

[ Flash Point ]:
204.3ºC

[ Exact Mass ]:
380.16200

[ PSA ]:
75.99000

[ LogP ]:
5.88590

[ Vapour Pressure ]:
1.94E-14mmHg at 25°C

[ Index of Refraction ]:
1.611

Related Compounds