JAK-IN-4

Names

[ CAS No. ]:
1400877-37-3

[ Name ]:
JAK-IN-4

Biological Activity

[Description]:

JAK-IN-4 is a prodrug of a JAK inhibitor, effective in murine collagen induced arthritis model[1].

[Related Catalog]:

Signaling Pathways >> JAK/STAT Signaling >> JAK
Signaling Pathways >> Epigenetics >> JAK
Signaling Pathways >> Stem Cell/Wnt >> JAK
Research Areas >> Inflammation/Immunology

[Target]

JAK


[References]

[1]. Spergel SH, et al. Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Med Chem Lett. 2019 Feb 13;10(3):306-311.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H19N4Na2O6P

[ Molecular Weight ]:
464.32

Related Compounds