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JAK-IN-4

Names

[ CAS No. ]:
1400877-37-3

[ Name ]:
JAK-IN-4

Biological Activity

[Description]:

JAK-IN-4 is a prodrug of a JAK inhibitor, effective in murine collagen induced arthritis model[1].

[Related Catalog]:

Signaling Pathways >> JAK/STAT Signaling >> JAK

Signaling Pathways >> Epigenetics >> JAK

Signaling Pathways >> Stem Cell/Wnt >> JAK

Research Areas >> Inflammation/Immunology

[Target]

JAK

[References]

[1]. Spergel SH, et al. Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Med Chem Lett. 2019 Feb 13;10(3):306-311.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₉N₄Na₂O₆P

[ Molecular Weight ]:
464.32

Related Compounds