TRV0109101

Names

[ Name ]:
TRV0109101

[Synonym ]:
2-[(9R)-9-(2-Pyridinyl)-6-oxaspiro[4.5]dec-9-yl]-N-(2-thienylmethyl)ethanamine
6-Oxaspiro[4.5]decane-9-ethanamine, 9-(2-pyridinyl)-N-(2-thienylmethyl)-, (9R)-

Biological Activity

[Description]:

A selective, G protein-biased µ-opioid receptor agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.

[References]

References 1. Koblish M, et al. J Pharmacol Exp Ther. 2017 Aug;362(2):254-262. View Related Products by Target Opioid Receptor

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
504.1±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₁H₂₈N₂OS

[ Molecular Weight ]:
356.525

[ Flash Point ]:
258.7±27.3 °C

[ Exact Mass ]:
356.192230

[ LogP ]:
3.53

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.597

TRV0109101

Names

Biological Activity

Chemical & Physical Properties

Related Compounds