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Trk-IN-1

Names

[ CAS No. ]:
1402438-37-2

[ Name ]:
Trk-IN-1

Biological Activity

[Description]:

Trk-IN-1 (example 9), a potent tropomyosin-related kinase (Trk) inhibitor, shows potency against TrkA (3.7 nM) and TrkB (94 nM), respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Trk Receptor

Research Areas >> Neurological Disease

[References]

[1]. Mark David Andrews, et al. Pyrrolo [2, 3 -d] pyrimidine derivatives as inhibitors of tropomyosin- related kinases. WO2012137089A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₀F₃N₅O₃

[ Molecular Weight ]:
483.44

Related Compounds