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Oligomycin D

Names

[ CAS No. ]:
1404-59-7

[ Name ]:
Oligomycin D

[Synonym ]:
Rutamycine [INN-French]
Rutamycinum [INN-Latin]
26-Demethyloligomycin A
Rutamicina [INN-Spanish]
RUTAMYCIN
rutamycin A
oligomycin D
Antibiotic A 272
A 272

Biological Activity

[Description]:

Oligomycin D (Rutamycin A) is an antibiotic. Oligomycin D can be derived from a strain of S. rutgersensis. Oligomycin D also is a potent inhibitors of K-Ras PM localization. Oligomycin D can be used for the research of various cancers[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[References]

[1]. Salim AA, et al. Oligomycins as inhibitors of K-Ras plasma membrane localisation. Org Biomol Chem. 2016 Jan 14;14(2):711-715.

Chemical & Physical Properties

[ Density]:
1.15g/cm3

[ Boiling Point ]:
883.4ºC at 760 mmHg

[ Molecular Formula ]:
C44H72O11

[ Molecular Weight ]:
777.04

[ Flash Point ]:
253ºC

[ Exact Mass ]:
776.50700

[ PSA ]:
180.05000

[ LogP ]:
5.63660

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.544

Safety Information

[ RIDADR ]:
UN 2811

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Related Compounds