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7-Oxabicyclo[4.1.0]heptane-3-carboxylicacid, 4-methyl-, (4-methyl-7-oxabicyclo[4.1.0]hept-3-yl)methyl ester

Names

[ CAS No. ]:
141-37-7

[ Name ]:
7-Oxabicyclo[4.1.0]heptane-3-carboxylicacid, 4-methyl-, (4-methyl-7-oxabicyclo[4.1.0]hept-3-yl)methyl ester

[Synonym ]:
Unox epoxide 201
CCRIS 279
Chissonox 201
4,5-epoxy-2-methyl-cyclohexanecarboxylic acid-(4,5-epoxy-2-methyl-cyclohexylmethyl ester)
4,5-Epoxy-2-methyl-cyclohexancarbonsaeure-(4,5-epoxy-2-methyl-cyclohexylmethylester)
Unox 201
EP 201
Epoxide-201

Chemical & Physical Properties

[ Density]:
1.139g/cm3

[ Boiling Point ]:
376.2ºC at 760mmHg

[ Molecular Formula ]:
C16H24O4

[ Molecular Weight ]:
280.35900

[ Flash Point ]:
164.4ºC

[ Exact Mass ]:
280.16700

[ PSA ]:
51.36000

[ LogP ]:
2.15660

[ Vapour Pressure ]:
7.36E-06mmHg at 25°C

[ Index of Refraction ]:
1.505

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RN7700000
CHEMICAL NAME :
7-Oxabicyclo(4.1.0)heptane-3-carboxylic acid, 4-methyl-, (4-methyl-7-oxabicyclo(4.1.0) hept-3-yl)methyl ester
CAS REGISTRY NUMBER :
141-37-7
BEILSTEIN REFERENCE NO. :
0246264
LAST UPDATED :
199612
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C16-H24-O4
MOLECULAR WEIGHT :
280.40
WISWESSER LINE NOTATION :
T36 BOTJ F1 EVO1- ET36 BOTJ F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4920 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 6/8/1965
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>10 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 6/8/1965 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
67 gm/kg/56W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 39,1217,1967
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
516 gm/kg/43W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 24,305,1963 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 11,147,1976 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 11,147,1976 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Synthetic Route

Precursor & DownStream


Related Compounds