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MDM2-IN-1

Names

[ CAS No. ]:
1410737-09-5

[ Name ]:
MDM2-IN-1

Biological Activity

[Description]:

MDM2-IN-1 (Compound 30) is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Apoptosis >> MDM-2/p53

[References]

[1]. Aguilar A, et al. Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro-mannich ring-opening-cyclization reaction mechanism in spiro-oxindoles. J Med Chem. 2014 Dec 26;57(24):10486-98.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₁Cl₂FN₂O₃

[ Molecular Weight ]:
463.33

Related Compounds