Fenazaflor

Names

[ Name ]:
Fenazaflor

[Synonym ]:
LOVOZAL
Caswell No. 654A
Lavozal
phenyl 5,6-dichloro-2-trifluoromethylbenzimidazole-1-carboxylate
Fenazaflor
phenyl 5,6-dichloro-2-(trifluoromethyl)-1H-1,3-benzimidazole-1-carboxylate
5,5-Dichloro-1-phenoxycarbonyl-2-trifluormethylbenzimidazol
Fisons NC 5016
Fenozaflor
Fenzaflor
EINECS 238-134-9
Tarzol
MFCD00055497
5,6-dichloro-2-trifluoromethyl-benzoimidazole-1-carboxylic acid phenyl ester
phenyl 5,6-dichloro-2-(trifluoromethyl)benzimidazole-1-carboxylate
Fenoflurazole
phenyl 5,6-dichloro-2-(trifluoromethyl)-1H-benzimidazole-1-carboxylate

Chemical & Physical Properties

[ Density]:
1.55g/cm3

[ Boiling Point ]:
434.3ºC at 760mmHg

[ Molecular Formula ]:
C₁₅H₇Cl₂F₃N₂O₂

[ Molecular Weight ]:
375.12900

[ Flash Point ]:
216.4ºC

[ Exact Mass ]:
373.98400

[ PSA ]:
44.12000

[ LogP ]:
5.40900

[ Vapour Pressure ]:
9.59E-08mmHg at 25°C

[ Index of Refraction ]:
1.603

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DD6650000

CHEMICAL NAME :: 1-Benzimidazolecarboxylic acid, 5,6-dichloro-2-(trifluoromethyl)-, phenyl ester

CAS REGISTRY NUMBER :: 14255-88-0

BEILSTEIN REFERENCE NO. :: 0964952

LAST UPDATED :: 199612

DATA ITEMS CITED :: 18

MOLECULAR FORMULA :: C15-H7-Cl2-F3-N2-O2

MOLECULAR WEIGHT :: 375.14

WISWESSER LINE NOTATION :: T56 BN DNJ BVOR& CXFFF GG HG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 240 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 168 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 42 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: >50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 28 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - pig

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 260 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - domestic

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 3717 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - altered sleep time (including change in righting reflex) Skin and Appendages - hair

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 283 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA repair

TEST SYSTEM :: Bacteria - Escherichia coli

DOSE/DURATION :: 500 ug/disc

REFERENCE :: JPFCD2 Journal of Environmental Science and Health, Part B: Pesticides, Food Contaminants, and Agricultural Wastes. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.B11- 1976- Volume(issue)/page/year: 21,319,1986 *** REVIEWS *** TOXICOLOGY REVIEW MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 32,151,1975

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H410

[ Precautionary Statements ]:
P273-P280-P501

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;N: Dangerous for the environment;

[ Risk Phrases ]:
21/22-50/53

[ Safety Phrases ]:
S60;S61;S36/S37

[ RIDADR ]:
UN2811 6.1/PG 3

[ RTECS ]:
DD6650000

[ HS Code ]:
2933990012

Customs

[ HS Code ]: 2933990012

[ Summary ]:
2933990012. VAT:17.0%. Tax rebate rate:9.0%. Supervision conditions:S(import or export registration certificate for pesticides). MFN tariff:6.5%. General tariff:20.0%

Articles

[Study of the effect of phenophtorazole on the calcium ion concentration in rat thymocyte cytoplasm and on changes of this parameter, induced by concanavalin A].

Dokl. Akad. Nauk. SSSR 317(2) , 499-502, (1991)

[Effect of inhibitors of lipoxygenase oxidation of arachidonic acid and phenofluorazole on rat thymocyte cytoplasmic pH and on the change of this parameter induced by concanavalin A].

Dokl. Akad. Nauk. SSSR 325(4) , 869-73, (1992)