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NH2-PEG7

Names

[ CAS No. ]:
1425973-14-3

[ Name ]:
NH2-PEG7

[Synonym ]:
MFCD28385479
20-Amino-3,6,9,12,15,18-hexaoxaicosan-1-ol
3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20-amino-

Biological Activity

[Description]:

NH2-PEG7 is a PROTAC linker, which refers to the PEG composition. NH2-PEG7 can be used in the synthesis of the PROTAC PARP1 degrader iRucaparib-AP6[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[References]

[1]. Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec;15(12):1223-1231.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
427.3±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C14H31NO7

[ Molecular Weight ]:
325.398

[ Flash Point ]:
212.2±27.3 °C

[ Exact Mass ]:
325.210052

[ LogP ]:
-3.16

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.464

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds