<Suppliers Price>

macrocarpal C

Names

[ CAS No. ]:
142628-53-3

[ Name ]:
macrocarpal C

[Synonym ]:
2,4,6-Trihydroxy-5-{3-methyl-1-[(1aS,4aR,7R,7aS,7bS)-1a,7,7b-trimethyl-4-methylenedecahydro-1H-cyclopropa[e]azulen-7-yl]butyl}isophthalaldehyde
1,3-Benzenedicarboxaldehyde, 5-[1-[(1aS,4aR,7R,7aS,7bS)-decahydro-1a,7,7b-trimethyl-4-methylene-1H-cycloprop[e]azulen-7-yl]-3-methylbutyl]-2,4,6-trihydroxy-
2,4,6-Trihydroxy-5-{(1R)-3-methyl-1-[(1aR,4aR,7S,7aR,7bR)-1,1,7-trimethyl-4-methylenedecahydro-1H-cyclopropa[e]azulen-7-yl]butyl}isophthalaldehyde
1,3-Benzenedicarboxaldehyde, 5-[(1R)-1-[(1aR,4aR,7S,7aR,7bR)-decahydro-1,1,7-trimethyl-4-methylene-1H-cycloprop[e]azulen-7-yl]-3-methylbutyl]-2,4,6-trihydroxy-
macrocarpal-C
macrocarpal G
macrocarpal C

Biological Activity

[Description]:

Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Jack Ho Wong, et al. Antifungal mode of action of macrocarpal C extracted from Eucalyptus globulus Labill (Lan An) towards the dermatophyte Trichophyton mentagrophytes. Chin Med. 2015, 10, 34.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
503.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C28H38O5

[ Molecular Weight ]:
454.60

[ Flash Point ]:
272.6±26.6 °C

[ Exact Mass ]:
454.271912

[ PSA ]:
94.83000

[ LogP ]:
10.79

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.594

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds