L-703014

Names

[ CAS No. ]:
142638-79-7

[ Name ]:
L-703014

[Synonym ]:
l 703,014

Biological Activity

[Description]:

L-703014 is a fibrinogen receptor antagonist, with the IC50 of 94 nM, that acts as a novel parenteral and potential oral antithrombotic agent[1][2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. J S Barrett, et al. Pharmacokinetics and Pharmacodynamics of L-703,014, a Potent Fibrinogen Receptor Antagonist, After Intravenous and Oral Administration in the Dog. Pharm Res. 1994 Mar;11(3):426-31.  

[2]. R M Scarborough, et al. Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents. J Med Chem. 2000 Sep 21;43(19):3453-73.  

Chemical & Physical Properties

[ Density]:
1.2g/cm3

[ Boiling Point ]:
809.7ºC at 760mmHg

[ Molecular Formula ]:
C24H34N4O4

[ Molecular Weight ]:
442.55100

[ Flash Point ]:
443.5ºC

[ Exact Mass ]:
442.25800

[ PSA ]:
130.30000

[ LogP ]:
4.35550

[ Vapour Pressure ]:
1.06E-27mmHg at 25°C

[ Index of Refraction ]:
1.581

Related Compounds