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2,4-PyriMidinediaMine with linker

Names

[ CAS No. ]:
1430089-64-7

[ Name ]:
2,4-PyriMidinediaMine with linker

[Synonym ]:
N-{4-[(3-Aminopropyl)amino]phenyl}-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine
2,4-Pyrimidinediamine, N-[4-[(3-aminopropyl)amino]phenyl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)-
2,4-PyriMidinediaMine with linker

Biological Activity

[Description]:

2,4-Pyrimidinediamine with linker is a patent compound in WO2013055780A1, Page 71; multikinase inhibitor and has a -NH2 terminal linker for further synthesis.Simultaneous detection of multiple protein kinases in tissue samples in the diagnosis and treatment of diseaseBy Johnson, Gary; Duncan, James S.; Whittle, Martin C.; Jian, Jin From PCT Int. Appl. (2013), WO 2013055780 A1 20130418.

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. MULTIPLEXED KINASE INHIBITOR BEADS AND USES THEREOF. Patent Application WO/2013/055780 Kind Code: A1


[Related Small Molecules]

Nintedanib (BIBF 1120) | SU5416 | Apatinib Mesylate | PD173074 | Foretinib (GSK1363089) | SU 5402 | Linifanib (ABT-869) | Cediranib | Lucitanib | RAF265 (CHIR-265) | LY2784544 | SU14813 | Dovitinib (TKI-258, CHIR-258) | SAR131675 | Vatalanib (PTK787) 2HCl

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
693.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H24N8

[ Molecular Weight ]:
364.448

[ Flash Point ]:
373.2±34.3 °C

[ Exact Mass ]:
364.212402

[ LogP ]:
0.92

[ Appearance of Characters ]:
off white solid

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.757

[ Storage condition ]:
-20℃

Related Compounds