[Asu1,6]-Oxytocin

[Asu1,6]-Oxytocin is an analog of oxytocin. [Asu1,6]-Oxytocin reverses insulin resistance and glucose intolerance prior to reduction of obesity. [Asu1,6]-Oxytocin has the potential for the research of obesity and diabetes[1].

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[Asu1,6]-Oxytocin (4 μg per injection; third-ventricle injection, twice injected for 7 days) 改善小鼠的葡萄糖耐受不良并降低空腹血胰岛素水平[1]。 Animal Model: C57BL/6 mice[1] Dosage: 4 μg per injection Administration: Third-ventricle injection, twice injected for 7 days Result: Improved glucose intolerance and lowered fasting blood insulin levels, and both effects were independent of body weight.

[1]. Zhang H, et al. Treatment of obesity and diabetes using oxytocin or analogs in patients and mouse models. PLoS One. 2013 May 20;8(5):e61477.