A1AR antagonist 2

Names

[ CAS No. ]:
1441961-74-5

[ Name ]:
A1AR antagonist 2

Biological Activity

[Description]:

A1AR antagonist 2 (compound 18h) is a potent A1 adenosine receptor (AR) antagonist with Kis of 1.49, 10.2, and 50.1 nM for hA1, hA2A and hA2B, respectively[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor

[References]

[1]. Val C, et al. Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1 Antagonists. J Med Chem. 2022;65(3):2091-2106.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₂N₄O

[ Molecular Weight ]:
288.30

A1AR antagonist 2

Names

Biological Activity

Chemical & Physical Properties

Related Compounds