Ethanamine,N,N-diethyl-2-[2-(2-methyl-5-phenyl-1H-pyrrol-1-yl)phenoxy]-, hydrochloride(1:1)
Names
[ CAS No. ]:
14435-78-0
[ Name ]:
Ethanamine,N,N-diethyl-2-[2-(2-methyl-5-phenyl-1H-pyrrol-1-yl)phenoxy]-, hydrochloride(1:1)
[Synonym ]:
1-[2-(2-Diaethylamino-aethoxy)-phenyl]-2-methyl-5-phenyl-pyrrol
1-(2-<2-Diethylamino-ethoxy>-phenyl)-2-methyl-5-phenyl-pyrrol
Leiopyrrole
Pyrrole,1-(o-(2-(diethylamino)ethoxy)phenyl)-2-methyl-5-phenyl
Leiopirrol [INN-Spanish]
Ethanamine,N,N-diethyl-2-(2-(2-methyl-5-phenyl-1H-pyrrol-1-yl)phenoxy)
Leiopirrol
1-[2-(2-Diaethylamino-aethoxy)-phenyl]-2-methyl-5-phenyl-pyrrol,Hydrochlorid
1-[2-(2-diethylamino-ethoxy)-phenyl]-2-methyl-5-phenyl-pyrrole,hydrochloride
Leiopyrrolum [INN-Latin]
1-(o-(2-(Diethylamino)ethoxy)phenyl)-2-methyl-5-phenylpyrrole
2-Methyl-5-phenyl-1-<2-(2-diethylamino-ethoxy)-phenyl>-pyrrol
1-[2-(2-diethylamino-ethoxy)-phenyl]-2-methyl-5-phenyl-pyrrole
DV 714
Leioplegil
Chemical & Physical Properties
[ Density]:
1.01g/cm3
[ Boiling Point ]:
497.9ºC at 760mmHg
[ Molecular Formula ]:
C23H29ClN2O
[ Molecular Weight ]:
384.94200
[ Flash Point ]:
254.9ºC
[ Exact Mass ]:
384.19700
[ PSA ]:
17.40000
[ LogP ]:
5.97530
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UX9465070
- CHEMICAL NAME :
- Pyrrole, 1-(o-(2-(diethylamino)ethoxy)phenyl)-2-methyl-5-pheny l-, monohydrochloride
- CAS REGISTRY NUMBER :
- 14435-78-0
- LAST UPDATED :
- 199603
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C23-H28-N2-O.Cl-H
- MOLECULAR WEIGHT :
- 384.99
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 17,287,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 185 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 17,287,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 475 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 17,287,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 115 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 19,753,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 28 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 17,287,1962