6-methyl-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one

Names

[ CAS No. ]:
144485-89-2

[ Name ]:
6-methyl-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one

Chemical & Physical Properties

[ Density]:
1.28g/cm3

[ Boiling Point ]:
543.3ºC at 760 mmHg

[ Molecular Formula ]:
C19H15N3O2

[ Molecular Weight ]:
317.34100

[ Flash Point ]:
282.4ºC

[ Exact Mass ]:
317.11600

[ PSA ]:
60.92000

[ LogP ]:
3.65750

[ Vapour Pressure ]:
7.28E-12mmHg at 25°C

[ Index of Refraction ]:
1.667

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA3680000
CHEMICAL NAME :
4(3H)-Quinazolinone, 6-methyl-3-(3-methyl-5-isoxazolyl)-2-phenyl-
CAS REGISTRY NUMBER :
144485-89-2
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H15-N3-O2
MOLECULAR WEIGHT :
317.37

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992

Synthetic Route

Precursor & DownStream


Related Compounds