Licochalcone D

Names

[ Name ]:
Licochalcone D

[Synonym ]:
UNII-3P0SH94V09
Licochalcone D

Biological Activity

[Description]:

Licochalcone D, a flavonoid compound mainly existing in the root of Glycyrrhiza inflate, is a potent inhibitor of NF-kappaB (NF-κB) p65. Licochalcone D possesses antioxidant, anti-inflammatory, anti-cancer properties[1][2].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

Research Areas >> Metabolic Disease

[Target]

p65

[References]

[1]. Furusawa J, et al. Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway. Int Immunopharmacol. 2009 Apr;9(4):499-507.

[2]. Si L, et al. Licochalcone D induces apoptosis and inhibits migration and invasion in human melanoma A375 cells. Oncol Rep. 2018 May;39(5):2160-2170.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₂O₅

[ Molecular Weight ]:
354.39600

[ Exact Mass ]:
354.14700

[ PSA ]:
86.99000

[ LogP ]:
4.21680

[ Storage condition ]:
2-8℃

Licochalcone D

Names

Biological Activity

Chemical & Physical Properties

Related Compounds