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5'-O-DMT-2'-ara-F-2'-dU

Names

[ CAS No. ]:
144822-63-9

[ Name ]:
5'-O-DMT-2'-ara-F-2'-dU

[Synonym ]:
5'-O-DMT-2'-ara-F-2'-dU

Biological Activity

[Description]:

5’-O-DMT-2’-deoxy-2’-fluoro-β-D-arabinouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.  

Chemical & Physical Properties

[ Density]:
1.38

[ Molecular Formula ]:
C29H27FN2O7

[ Molecular Weight ]:
534.53

[ Exact Mass ]:
548.19600

[ PSA ]:
112.01000

[ LogP ]:
3.15890

[ Index of Refraction ]:
1.647

[ Storage condition ]:
2-8℃


Related Compounds