Naquotinib mesylate
Names
[ CAS No. ]:
1448237-05-5
[ Name ]:
Naquotinib mesylate
[Synonym ]:
6-Ethyl-3-{4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino}-5-{[(3R)-1-(prop-2-enoyl)pyrrolidin-3-yl]oxy}pyrazine-2-carboxamide monomethanesulfonate
6-ethyl-3-({4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-5-{[(3R)-1-(1-oxoprop-2-en-1-yl)pyrrolidin-3-yl]oxy}pyrazine-2-carboxamide monomethanesulfonate
UNII-12T09LV21O
5-{[(3R)-1-Acryloyl-3-pyrrolidinyl]oxy}-6-ethyl-3-({4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl}amino)-2-pyrazinecarboxamide methanesulfonate (1:1)
ASP8273 mesilate
Naquotinib mesilate
Naquotinib mesylate
2-Pyrazinecarboxamide, 6-ethyl-3-[[4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[[(3R)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]oxy]-, methanesulfonate (1:1)
12T09LV21O
Naquotinib (mesylate)
Biological Activity
[Description]:
[Related Catalog]:
[Target]
EGFRL858R/T790M
EGFRL858R
EGFRExon 19 deletion
EGFRExon 19 deletion/T790M
EGFR:230 nM (IC50)
[In Vitro]
[In Vivo]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Molecular Formula ]:
C31H46N8O6S
[ Molecular Weight ]:
658.812
[ Exact Mass ]:
658.326111
[ Storage condition ]:
2-8℃