Tos-PEG4-acid

Names

[ CAS No. ]:
1453117-42-4

[ Name ]:
Tos-PEG4-acid

[Synonym ]:
MFCD29052202

Biological Activity

[Description]:

Tos-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₂₄O₈S

[ Molecular Weight ]:
376.42

Tos-PEG4-acid

Names

Biological Activity

Chemical & Physical Properties

Related Compounds