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Bisindolylmaleimide X HCl

Names

[ CAS No. ]:
145317-11-9

[ Name ]:
Bisindolylmaleimide X HCl

[Synonym ]:
3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione hydrochloride (1:1)
1H-Pyrrole-2,5-dione, 3-[8-(aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-, hydrochloride (1:1)
3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione hydrochloride

Biological Activity

[Description]:

Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent protein kinase C (PKC) inhibitor[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> PKC
Research Areas >> Others
Signaling Pathways >> TGF-beta/Smad >> PKC

[Target]

PKC


[References]

[1]. Brehmer D, et al. Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors. Mol Cell Proteomics. 2004 May;3(5):490-500.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H25ClN4O2

[ Molecular Weight ]:
460.955

[ Exact Mass ]:
460.166595

Related Compounds