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SAH-EZH2

Names

[ CAS No. ]:
1453222-26-8

[ Name ]:
SAH-EZH2

Biological Activity

[Description]:

SAH-EZH2 is an EZH2/EPP interaction inhibitor (Kd = 320 nM). SAH-EZH2 suppresses EZH2 expression and H3K27 trimethylation by PCR2 complex. SAH-EZH2 arrests proliferation and induces monocyte to macrophage differentiation of MLL-AF9 leukemia cell line.

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Histone Methyltransferase

Chemical & Physical Properties

[ Molecular Formula ]:
C155H256N48O40

[ Molecular Weight ]:
3432.05


Related Compounds