Mastoparan 17

Names

[ Name ]:
Mastoparan 17

[Synonym ]:
INLKAKAALAKKLL-NH2
H-ILE-ASN-LEU-LYS-ALA-LYS-ALA-ALA-LEU-ALA-LYS-LYS-LEU-LEU-OH
H-Ile-Asn-Leu-Lys-Ala-Lys-Ala-Ala-Leu-Ala-Lys-Lys-Leu-Leu-NH2
ILE-ASN-LEU-LYS-ALA-LYS-ALA-ALA-LEU-ALA-LYS-LYS-LEU-LEU-NH2
MAS 17

Biological Activity

[Description]:

Mastoparan 17 is a tetradecapeptide. Mastoparan 17 is an inactive analogue of Mastoparan (HY-P0246) [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

Chemical & Physical Properties

[ Molecular Formula ]:
C₇₀H₁₃₂N₂₀O₁₅

[ Molecular Weight ]:
1493.92000

[ Exact Mass ]:
1493.02000

[ PSA ]:
594.58000

[ LogP ]:
6.78670

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

Articles

Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity.

J. Biol. Chem. 265 , 14176, (1990)

Mastoparan (MP), a cationic, amphiphilic tetradecapeptide, stimulates guanine nucleotide exchange by GTP-binding regulatory proteins (G proteins) in a manner similar to that of G protein-coupled recep...

Exocytosis in chromaffin cells: evidence for a MgATP-independent step that requires a pertussis toxin-sensitive GTP-binding protein.

Biochem. J. 15 , 217-227, (1994)

We have previously described that mastoparan, an amphiphilic tetradecapeptide that activates heterotrimeric G-proteins, inhibits Ca(2+)-induced MgATP-dependent secretion from streptolysin-O-permeabili...

Evidence of heterotrimeric G-protein involvement in regulated exocytosis from permeabilized pancreatic acini.

Pancreas 10 , 374, (1995)

Constitutive membrane trafficking events are regulated by heterotrimeric G-proteins (G-proteins) in addition to their regulation by small GTP-binding proteins (smgs). Here, we used streptolysin O-perm...