selegiline

Names

[ Name ]:
selegiline

[Synonym ]:
Eldepryl
Jumex
(2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine
N-methyl-N-((R)-1-phenylpropan-2-yl)prop-2-yn-1-amine
Selegilina
Emsam
L-Deprenalin
Carbex
methyl(1-phenylpropan-2-yl)(prop-2-yn-1-yl)amine
Selegilinum
(S)-(+)-selegiline
Selegyline
Zelapar

Chemical & Physical Properties

[ Density]:
0.954g/cm3

[ Boiling Point ]:
272.5ºC at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₇N

[ Molecular Weight ]:
187.28100

[ Flash Point ]:
108.4ºC

[ Exact Mass ]:
187.13600

[ PSA ]:
3.24000

[ LogP ]:
2.18260

[ Vapour Pressure ]:
0.00606mmHg at 25°C

[ Index of Refraction ]:
1.528

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311

[ Hazard Codes ]:
F,T

[ Risk Phrases ]:
11-23/24/25-39/23/24/25

[ Safety Phrases ]:
7-16-36/37-45

[ RIDADR ]:
UN 1851

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2921499090

Customs

[ HS Code ]: 2921499090

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Design and application of an in vivo reporter assay for phenylalanine ammonia-lyase.

Appl. Microbiol. Biotechnol. 97(17) , 7877-85, (2013)

Phenylalanine ammonia-lyase (PAL) is an important enzyme that links primary metabolism to secondary metabolism. Its efficiency is often a critical factor that affects the overall flux of a related met...

A (p)ppGpp-null mutant of Haemophilus ducreyi is partially attenuated in humans due to multiple conflicting phenotypes.

Infect. Immun. 82(8) , 3492-502, (2014)

(p)ppGpp responds to nutrient limitation through a global change in gene regulation patterns to increase survival. The stringent response has been implicated in the virulence of several pathogenic bac...

Mutational analysis of the (p)ppGpp synthetase activity of the Rel enzyme of Mycobacterium tuberculosis.

Arch. Microbiol. 196(8) , 575-88, (2014)

Rel(Mtb), a GTP pyrophosphokinase encoded by the Mycobacterium tuberculosis (Mtb) genome, catalyzes synthesis of (p)ppGpp from ATP and GDP(GTP) and its hydrolysis to GDP(GTP) and pyrophosphate to medi...