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Azido-C6-OH

Names

[ CAS No. ]:
146292-90-2

[ Name ]:
Azido-C6-OH

[Synonym ]:
1-Hexanol,6-azido
6-azido-hexanol
6-azido-hexan-1-ol
6-azidohexane-1-ol
6-Azido-1-hexanol

Biological Activity

[Description]:

Azido-C6-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C6H13N3O

[ Molecular Weight ]:
143.18700

[ Exact Mass ]:
143.10600

[ PSA ]:
69.98000

[ LogP ]:
1.30216

Synthetic Route

Precursor & DownStream


Related Compounds