N-1-Naphthylethylenediamine dihydrochloride

Names

[ Name ]:
N-1-Naphthylethylenediamine dihydrochloride

[Synonym ]:
N-(1-naphthyl)-ethylenediamine dihydrochloride
N-(1-naphthyl) ethylenediamine dihydrochloride
N-(1-Naphthyl)ethane-1,2-diamine dihydrochloride
N-(1-Naphthyl)ethylenediamine 2HCl
N-(1-Naphthyl)-1,2-ethanediamine dihydrochloride
N-(1-naphthyl)ethylene-1,2-diamine dihydrochloride
N-(1-Naphthyl)ethylenediamine,dihydrochlo
Bratton Marshall reagent
Monomethanolate
EINECS 215-981-2
N-(1-Naphthyl)ethylenediamine,dihydrochloride
MFCD00012556
1,2-Ethanediamine, N-1-naphthalenyl-, hydrochloride (1:2)
N-(1-Naphthyl)ethylenediamine dihydrochloride
MARSHALL'S REAGENT
N-(1-naphthyl)-1,2-ethylenediamine dihydrochloride
Bratton-Marshall Reage
N-(2-aminoethyl)naphthalen-1-amine dihydrochloride
Bratton-Marshall
N-(1-Naphthyl)ethyle
BRATTON'S REAGENT
N-1-Naphthylethylenediamine dihydrochloride
N1-(naphthalen-1-yl)ethane-1,2-diamine dihydrochloride
NED 2HCL

Chemical & Physical Properties

[ Boiling Point ]:
370.7ºC at 760 mmHg

[ Melting Point ]:
200 °C

[ Molecular Formula ]:
C₁₂H₁₆Cl₂N₂

[ Molecular Weight ]:
259.175

[ Flash Point ]:
209.7ºC

[ Exact Mass ]:
258.069061

[ PSA ]:
38.05000

[ LogP ]:
4.58770

[ Vapour Pressure ]:
1.08E-05mmHg at 25°C

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KV5330000

CHEMICAL NAME :: Ethylenediamine, N-(1-naphthyl)-, dihydrochloride

CAS REGISTRY NUMBER :: 1465-25-4

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C12-H14-N2.2Cl-H

MOLECULAR WEIGHT :: 259.20

WISWESSER LINE NOTATION :: L66J BM2Z &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 800 ug/plate

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl 7),1,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3681 No. of Facilities: 214 (estimated) No. of Industries: 5 No. of Occupations: 7 No. of Employees: 3452 (estimated) No. of Female Employees: 1660 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S36/37-S45-S37/39-S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
KV5330000

[ Packaging Group ]:
I; II; III

[ Hazard Class ]:
6.1

[ HS Code ]:
29215990

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921590090

[ Summary ]:
2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Chondroprotective effects of a new glucosamine combination in rats: Gene expression, biochemical and histopathological evaluation.

Life Sci. 130 , 31-7, (2015)

This study investigates the effect of a new combination of glucosamine hydrochloride, chondroitin sulfate, methylsulfonylmethane, Harpagophytum procumbens root extract (standardized to 3% harpagoside)...

Modulation of cytochrome P450 2A5 activity by lipopolysaccharide: low-dose effects and non-monotonic dose-response relationship.

PLoS ONE 10(1) , e0117842, (2015)

Mouse cytochrome P450 (CYP) 2A5 is induced by inflammatory conditions and infectious diseases that down-regulate the expression and activity of most other CYP isoforms. Enhanced oxidative stress and n...

N-(1-naphthyl) ethylenediamine dinitrate: a new matrix for negative ion MALDI-TOF MS analysis of small molecules.

J. Am. Soc. Mass Spectrom. 23(9) , 1454-60, (2012)

An organic salt, N-(1-naphthyl) ethylenediamine dinitrate (NEDN), with rationally designed properties of a strong UV absorbing chromophore, hydrogen binding and nitrate anion donors, has been employed...