<Suppliers Price>

Alatrofloxacin

Names

[ CAS No. ]:
146961-76-4

[ Name ]:
Alatrofloxacin

[Synonym ]:
7495
Alatrofloxacin
L-Alaninamide, L-alanyl-N-[(1R,5S)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-
7QVV6I50DT
L-Alanyl-N-{(1R,5S,6s)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5-oxo-5,8-dihydro-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl}-L-alaninamide

Biological Activity

[Description]:

Alatrofloxacin, the parenteral prodrug of Trovafloxacin, is a fluoronaphthyridone which contains an L-alanyl-L-alanyl salt. Alatrofloxacin functions similar to other fluoroquinolone antibiotics in that it not only has antibiotic activity to kill invading organisms by interfering with DNA synthesis, it possesses immunosuppressive activity[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[References]

[1]. Hall IH, et al. Effects of alatrofloxacin, the parental prodrug of trovafloxacin, on phagocytic, anti-inflammatory and immunomodulation events of human THP-1 monocytes. Biomed Pharmacother. 2003;57(8):359-365.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
863.2±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H25F3N6O5

[ Molecular Weight ]:
558.509

[ Flash Point ]:
475.8±34.3 °C

[ Exact Mass ]:
558.183838

[ LogP ]:
0.33

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.673

Related Compounds