N-Methylcoclaurine

Names

[ Name ]:
N-Methylcoclaurine

[Synonym ]:
(+/-)-N-methylcoclaurine
1-(4-hydroxy-benzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-7-ol
(+/-)-1-(4-Hydroxy-benzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydro-isochinolin-7-ol
rac-N-Methyl-coclaurin,(+/-)-1-(p-Hydroxy-benzyl)-2-methyl-6-methoxy-7-hydroxy-1,2,3,4-tetrahydro-isochinolin

Biological Activity

[Description]:

(±)-N-Methylcoclaurine is a selective α2-adrenoceptor antagonist[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

[References]

[1]. H H Pauli, et al. Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3'-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis. Plant J. 1998 Mar;13(6):793-801.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₂₁NO₃

[ Molecular Weight ]:
299.36

[ Exact Mass ]:
299.15200

[ PSA ]:
52.93000

[ LogP ]:
2.81600

N-Methylcoclaurine

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds