ICI D1542

Names

[ Name ]:
ICI D1542

[Synonym ]:
ici-d 1542
zd 1542

Biological Activity

[Description]:

ICI D1542 is a selective and potent inhibitor of thromboxane A2 (TXA2) synthase and the thromboxane A2 receptor (TP-receptor). ICI D1542 is effective at preventing thrombus formation by redirection of arachidonic acid metabolism[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

[References]

[1]. S J McAuliffe, et al. Redirection of arachidonic acid metabolism by ICI D1542: effects on thrombus formation in the coronary artery of the anaesthetized dog. r J Pharmacol. 1993 Apr;108(4):901-6.

Chemical & Physical Properties

[ Density]:
1.225g/cm3

[ Boiling Point ]:
661.1ºC at 760 mmHg

[ Molecular Formula ]:
C₂₅H₃₀N₂O₇

[ Molecular Weight ]:
470.51500

[ Flash Point ]:
353.6ºC

[ Exact Mass ]:
470.20500

[ PSA ]:
123.70000

[ LogP ]:
5.52030

[ Vapour Pressure ]:
2.22E-18mmHg at 25°C

[ Index of Refraction ]:
1.563