m-PEG4-O-NHS ester
Names
[ CAS No. ]:
147912-03-6
[ Name ]:
m-PEG4-O-NHS ester
[Synonym ]:
carbonic acid 2,5-dioxo-pyrrolidin-1-yl ester 2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethyl ester
Biological Activity
[Description]:
m-PEG4-O-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Related Catalog]:
[Target]
PEGs
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C14H23NO9
[ Molecular Weight ]:
349.33400
[ Exact Mass ]:
349.13700
[ PSA ]:
109.83000