BRD 8430

Names

[ Name ]:
BRD 8430

Biological Activity

[Description]:

BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively; shows no activity against other HDACs; decreases viability and induces differentiation of neuroblastoma cell lines.

[References]

References 1. Frumm SM, et al. Chem Biol. 2013 May 23;20(5):713-25. View Related Products by Target HDAC

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₃H₄₃N₅O₄

[ Molecular Weight ]:
573.738

Related Compounds

BRD-IN-26
brd-in-3
BRD 8184
BRD 8899
BRD 0476
BRD-4592
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1-(4-(Pyridin-4-yloxy)piperidin-1-yl)-2-(thiophen-3-yl)ethanone
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
N1-(3,4-difluorophenyl)-N2-((1-hydroxy-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)methyl)oxalamide
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine