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CGP 54626 hydrochloride

Names

[ CAS No. ]:
149184-21-4

[ Name ]:
CGP 54626 hydrochloride

Biological Activity

[Description]:

CGP 54626 (hydrochloride) is a selective antagonist of GABAB receptor with an IC50 value of 4 nM. CGP 54626 (hydrochloride) can be used to investigate the role of GABAB receptors in neurological signaling[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor
Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> GABA Receptor

[References]

[1]. Kaupmann K, et al. GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature. 1998 Dec 17;396(6712):683-7.

Chemical & Physical Properties

[ Boiling Point ]:
632.4ºC at 760mmHg

[ Molecular Formula ]:
C18H29Cl3NO3P

[ Molecular Weight ]:
444.76100

[ Flash Point ]:
336.3ºC

[ Exact Mass ]:
443.09500

[ PSA ]:
79.37000

[ LogP ]:
6.04850

[ Vapour Pressure ]:
7.3E-17mmHg at 25°C

Related Compounds