O-SUCCINYL-L-HOMOSERINE

Names

[ Name ]:
O-SUCCINYL-L-HOMOSERINE

[Synonym ]:
(2S)-2-amino-4-(3-carboxypropanoyloxy)butanoic acid
O-Succinyl-L-homoserine

Biological Activity

[Description]:

O-Succinyl-L-homoserine is a homoserine derivative. O-Succinyl-L-homoserine is an intermediate in the biosynthesis of methionine in Escherichia coli and Salmonella typhimurium[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Huang JF, et, al. Metabolic engineering of E. coli for the production of O-succinyl-l-homoserine with high yield. 3 Biotech. 2018 Jul;8(7):310.

Chemical & Physical Properties

[ Density]:
1.392g/cm3

[ Boiling Point ]:
492.8ºC at 760mmHg

[ Molecular Formula ]:
C₈H₁₃NO₆

[ Molecular Weight ]:
219.19200

[ Flash Point ]:
251.8ºC

[ Exact Mass ]:
219.07400

[ PSA ]:
126.92000

[ Vapour Pressure ]:
4.68E-11mmHg at 25°C

[ Index of Refraction ]:
1.515

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922509090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

The enzymology of cystathionine biosynthesis: strategies for the control of substrate and reaction specificity.

Arch. Biochem. Biophys. 433 , 166-175, (2005)

The ability of enzymes to catalyze specific reactions, while excluding others, is central to cellular metabolism. Control of reaction specificity is of particular importance for enzymes that employ ca...

Cloning and characterization of two Lactobacillus casei genes encoding a cystathionine lyase.

Appl. Environ. Microbiol. 74 , 99-106, (2008)

Volatile sulfur compounds are key flavor compounds in several cheese types. To better understand the metabolism of sulfur-containing amino acids, which certainly plays a key role in the release of vol...

Enzymatic characterization and inhibitor discovery of a new cystathionine {gamma}-synthase from Helicobacter pylori.

J. Biochem. 143 , 59-68, (2008)

Cystathionine gamma-synthase (CGS) catalyses the first step of the transsulfuration pathway that converts l-cysteine to l-homocysteine in bacteria, whereas this pathway is absent in human. In this rep...