Hydroxy-PEG2-CH2-Boc

Names

[ Name ]:
Hydroxy-PEG2-CH2-Boc

[Synonym ]:
2-Methyl-2-propanyl [2-(2-hydroxyethoxy)ethoxy]acetate
Acetic acid, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1,1-dimethylethyl ester
MFCD25959245

Biological Activity

[Description]:

Hydroxy-PEG2-CH2-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
306.1±22.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₂₀O₅

[ Molecular Weight ]:
220.263

[ Flash Point ]:
109.5±15.8 °C

[ Exact Mass ]:
220.131073

[ LogP ]:
0.47

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.445

Safety Information

[ Hazard Codes ]:
Xi

Hydroxy-PEG2-CH2-Boc

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Related Compounds