Spiro[2H-1-benzopyran-2,2'-[2H]indole],1',3'-dihydro-1',3',3'-trimethyl-6-nitro-
Names
[ CAS No. ]:
1498-88-0
[ Name ]:
Spiro[2H-1-benzopyran-2,2'-[2H]indole],1',3'-dihydro-1',3',3'-trimethyl-6-nitro-
[Synonym ]:
EINECS 216-102-5
1',3',3'-Trimethyl-6-nitrospiro[1(2H)-benzopyran-2,2'-indoline]
1,3,3-Trimethylindolino-6'-nitrobenzopyrylospiran [Photochromic Compound]
MFCD00059175
1',3',3'-trimethyl-6-nitrospiro[chromene-2,2'-indole]
Chemical & Physical Properties
[ Density]:
1.31g/cm3
[ Boiling Point ]:
476.3ºC at 760mmHg
[ Melting Point ]:
32ºC
[ Molecular Formula ]:
C19H18N2O3
[ Molecular Weight ]:
322.35800
[ Flash Point ]:
241.9ºC
[ Exact Mass ]:
322.13200
[ PSA ]:
58.29000
[ LogP ]:
4.71250
[ Vapour Pressure ]:
3.08E-09mmHg at 25°C
[ Index of Refraction ]:
1.67
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WG9870000
- CHEMICAL NAME :
- Spiro(2H-1-benzopyran-2,2'-indoline), 6-nitro-1',3',3'-trimethyl-
- CAS REGISTRY NUMBER :
- 1498-88-0
- BEILSTEIN REFERENCE NO. :
- 0040498
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C19-H18-N2-O3
- MOLECULAR WEIGHT :
- 322.39
- WISWESSER LINE NOTATION :
- T66 BOXJ HNW C-& CT56 BNX DHJ B1 D1 D1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#07770
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
26-37/39
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
WG9870000
[ HS Code ]:
2934999090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Ann. Biomed. Eng. 14(3) , 203-18, (1986)
A nonintrusive method for the visualization of pulsatile flow velocity profiles is described. The method is based on the use of a photochromic dye that is added to the fluid being studied and a nitrog...
Mast cells involvement in the inflammation and fibrosis development of the TNBS-induced rat model of colitis.Scand. J. Gastroenterol. 37(3) , 330-7, (2002)
Mast cells have been implicated in chronic inflammatory conditions resulting in fibrosis, such as Crohn disease. However, a link between inflammation, fibrosis and mast cells has not been demonstrated...
Direct structural determination of conformations of photoswitchable molecules by laser desorption-electron diffraction.Angew. Chem. Int. Ed. Engl. 49(37) , 6524-7, (2010)