β-Estradiol 3-(β-D-glucuronide) sodium salt
Names
[ CAS No. ]:
14982-12-8
[ Name ]:
β-Estradiol 3-(β-D-glucuronide) sodium salt
[Synonym ]:
Sodium (17β)-17-hydroxyestra-1,3,5(10)-trien-3-yl β-D-glucopyranosiduronate
β-D-Glucopyranosiduronic acid, (17β)-17-hydroxyestra-1,3,5(10)-trien-3-yl, sodium salt (1:1)
sodium,3,4,5-trihydroxy-6-[(17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl)oxy]oxane-2-carboxylic acid
Chemical & Physical Properties
[ Molecular Formula ]:
C24H31NaO8
[ Molecular Weight ]:
470.488
[ Exact Mass ]:
470.191650
[ PSA ]:
139.51000
[ Storage condition ]:
-20°C
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H332
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
20/21/22
[ Safety Phrases ]:
22-36
[ RIDADR ]:
NONH for all modes of transport
Articles
Biochem. J. 261(1) , 297-300, (1989)
By using rat liver perfusion under one-pass conditions with a single pulse of horseradish peroxidase (HRP), the biliary output of HRP was used as an indicator of paracellular permeability change cause...
Coregulation of C3-hydroxyl versus C17-hydroxyl glucuronidation of beta-estradiol in pregnancy and after treatment with phenobarbital or ethinyl-estradiol.J. Pharmacol. Exp. Ther. 246(1) , 54-9, (1988)
The glucuronidation of [3H]estradiol-17 beta at the C3 vs. the C17 hydroxyl groups was determined in female Sprague-Dawley rat liver microsomes. A high-performance liquid chromatography method was dev...
Inhibitory effects of commonly used herbal extracts on UGT1A1 enzyme activity.Xenobiotica 40(10) , 663-9, (2010)
Commonly used herbal supplements were screened for their potential to inhibit UGT1A1 activity using human liver microsomes. Extracts screened included ginseng, echinacea, black cohosh, milk thistle, g...