Pemetrexed
Names
[ CAS No. ]:
150399-23-8
[ Name ]:
Pemetrexed
[Synonym ]:
Alimt
disodium (2S)-2-[({4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]phenyl}carbonyl)amino]pentanedioate
PeMetexed DisodiuM
PEMETREXED SODIUM
(2S)-2-[({4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)éthyl]phényl}carbonyl)amino]pentanedioate de disodium
Disodium N-[p-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamate
N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt
L-Glutamic acid, N-(4-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-, disodium salt
Alimta
L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt (1:2)
PEMETREXED
MFCD07779402
Dinatrium-(2S)-2-[({4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]phenyl}carbonyl)amino]pentandioat
Pemetrexed disodium
L-glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt
Pemwtrexed Disodium
Pemetrexed Dinatrium
Pemetrexed (disodium)
Disodium (2S)-2-({4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}amino)pentanedioate
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Ki: 1.3 nM (TS), 7.2 nM (DHFR), 65 nM (GARFT)[1]
[In Vitro]
[In Vivo]
[Kinase Assay]
[Cell Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Boiling Point ]:
160°C 20mm
[ Melting Point ]:
36-38°C
[ Molecular Formula ]:
C20H19N5Na2O6
[ Molecular Weight ]:
471.374
[ Flash Point ]:
160°C/20mm
[ Exact Mass ]:
471.113068
[ PSA ]:
196.92000
[ Storage condition ]:
-20°C Freezer
Safety Information
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R36/38;R60;R61;R68
[ Safety Phrases ]:
36/37/39-53
[ HS Code ]:
2933990090
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%