(2H10)-1,2-Dihydroacenaphthylene

Names

[ Name ]:
(2H10)-1,2-Dihydroacenaphthylene

[Synonym ]:
Acenaphthene-d10
perdeuterioacenaphthene
Perdeuterioacenaphthen
MFCD00068265
d10-acenaphthene
(H)-1,2-Dihydroacenaphthylene
Acenaphthylene-d, 1,2-dihydro-d-
decadeuterio-acenaphthene
Acenaphthylene-d8,1,2-dihydro-d2
Deuteroacenaphthen
Perdeuteroacenaphthen

Biological Activity

[Description]:

Acenaphthene-d10 is the deuterium labeled Acenaphthene[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
279.0±0.0 °C at 760 mmHg

[ Melting Point ]:
95-97ºC(lit.)

[ Molecular Formula ]:
C₁₂D₁₀

[ Molecular Weight ]:
164.269

[ Flash Point ]:
135.3±9.7 °C

[ Exact Mass ]:
164.141022

[ LogP ]:
4.19

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.692

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335-H410

[ Precautionary Statements ]:
P261-P273-P305 + P351 + P338-P501

[ Target Organs ]:
Blood, Central nervous system, Liver

[ Hazard Codes ]:
T: Toxic;Xi: Irritant;N: Dangerous for the environment;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-37/39-36/37-24/25-23-53-45-61-60

[ RIDADR ]:
UN 3077 9

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

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