Bupropion D9

Names

[ Name ]:
Bupropion D9

[Synonym ]:
bupropion-d9
[2H9]-Bupropion
propion SR

Biological Activity

[Description]:

Bupropion D9 is a deuterium labeled Bupropion. Bupropion is an atypical antidepressant of the aminoketone group and inhibits dopamine, norepinephrine reuptake and blocks several nicotinic receptors[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor

Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor

Research Areas >> Neurological Disease

[In Vitro]

Major active metabolites of Bupropion, hydroxybupropion, threohydrobupropion, and erythrohydrobupropion reach higher plasma concentrations than bupropion[1].

[References]

[1]. Rafaela Costa, et al. Pharmacokinetic and Pharmacodynamic of Bupropion: Integrative Overview of Relevant Clinical and Forensic Aspects. Drug Metab Rev. 2019 Aug;51(3):293-313.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₉D₉ClNO

[ Molecular Weight ]:
248.79700

[ Exact Mass ]:
248.16400

[ PSA ]:
29.10000

[ LogP ]:
3.69020

Bupropion D9

Names

Biological Activity

Chemical & Physical Properties

Related Compounds