UCB-5307

Names

[ CAS No. ]:
1515887-44-1

[ Name ]:
UCB-5307

Biological Activity

[Description]:

UCB-5307 is a TNF signaling inhibitor with a KD of 9 nM. UCB-5307 can penetrate the preformed hTNF/hTNFR1 complex[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. O'Connell J, et al. Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer. Nat Commun. 2019 Dec 19;10(1):5795.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H21N3O

[ Molecular Weight ]:
343.42

Related Compounds