FL118
Names
Biological Activity
[Description]:
(R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118 (HY-12486). (R)-FL118 shows anticancer activity[1].
[Related Catalog]:
[In Vitro]
(R)-FL118 inhibits the growth of melanoma, breast, and prostate cancer cell lines, with IC50 values of 392.7, 32.53, 129.3, 138.7, and 92.51 ng/mL in B16, MCF-7, HS578T, DU145, and MPC3 cells, respectively[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C21H16N2O6
[ Molecular Weight ]:
392.36200
[ Exact Mass ]:
392.10100
[ PSA ]:
99.88000
[ LogP ]:
1.80830