β-glucuronidase substrate

Names

[ Name ]:
β-glucuronidase substrate

[Synonym ]:
(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[4-[1-(4-hydroxyphenyl)-3-oxo-2-benzofuran-1-yl]phenoxy]oxane-2-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.584g/cm3

[ Boiling Point ]:
804.5ºC at 760mmHg

[ Molecular Formula ]:
C₂₆H₂₂O₁₀

[ Molecular Weight ]:
494.44700

[ Flash Point ]:
276.5ºC

[ Exact Mass ]:
494.12100

[ PSA ]:
162.98000

[ LogP ]:
1.12550

[ Vapour Pressure ]:
2.53E-27mmHg at 25°C

[ Storage condition ]:
20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Deconjugation of glucuronides catalysed by UDPglucuronyltransferase.

Biochim. Biophys. Acta 873(2) , 252-9, (1986)

Evidence was found for UDPglucuronyltransferase-catalysed deconjugation of p-nitrophenol-, 4-methylumbelliferone- and phenolphthalein-glucuronides. The evidence is based on the following observations:...

Distribution of chlordecone to liver plasma membranes and recovery from hepatobiliary dysfunction in rats.

Toxicology 86(1-2) , 123-34, (1994)

Chlordecone (CD) impairs biliary excretion of organic anions (including phenolphthalein glucuronide (PG), imipramine polar metabolites, and taurocholate) without evidence of hepatocellular necrosis in...

NMR-monitored solid-phase extraction of phenolphthalein glucuronide on phenylboronic acid and C18 bonded phases.

J. Pharm. Biomed. Anal. 9(10-12) , 895-9, (1991)

Preliminary studies have been undertaken to evaluate the potential of immobilized phenylboronic acid (PBA) for the solid-phase extraction (SPE) of glucuronide metabolites from urine. These studies hav...