Dexamethasone 17-Propionate
Names
[ CAS No. ]:
15423-89-9
[ Name ]:
Dexamethasone 17-Propionate
[Synonym ]:
Dexamethasone propionate
Pregna-1,4-diene-3,20-dione,9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-,17-propionate
Dexamethason-17-propionat
Dexamethasone 17-propionate
9-Fluoro-11|A,17,21-trihydroxy-16|A-methyl-pregna-1,4-diene-3,20-dione 17-Propionate
Chemical & Physical Properties
[ Density]:
1.28g/cm3
[ Boiling Point ]:
579.5ºC at 760mmHg
[ Molecular Formula ]:
C25H33FO6
[ Molecular Weight ]:
448.52400
[ Flash Point ]:
304.3ºC
[ Exact Mass ]:
448.22600
[ PSA ]:
100.90000
[ LogP ]:
2.85660
[ Vapour Pressure ]:
7.68E-16mmHg at 25°C
[ Index of Refraction ]:
1.567
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU3836550
- CHEMICAL NAME :
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)- , (11-beta,16-alpha)-
- CAS REGISTRY NUMBER :
- 15423-89-9
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C25-H33-F-O6
- MOLECULAR WEIGHT :
- 448.58
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,666,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 36500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,666,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 26 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,666,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 7600 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,781,1995
Safety Information
[ HS Code ]:
2915900090
Customs
[ HS Code ]: 2915900090
[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%