Phenoxyacetic acid-d5

Names

[ CAS No. ]:
154492-74-7

[ Name ]:
Phenoxyacetic acid-d5

[Synonym ]:
2-(2,3,4,5,6-pentadeuteriophenoxy)acetic acid

Biological Activity

[Description]:

Phenoxyacetic acid-d5 is the deuterium labeled Phenoxyacetic acid[1]. Phenoxyacetic acid is an endogenous metabolite.

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.261g/cm3

[ Boiling Point ]:
285ºC at 760 mmHg

[ Molecular Formula ]:
C₈H₃D₅O₃

[ Molecular Weight ]:
157.17800

[ Flash Point ]:
115.1ºC

[ Exact Mass ]:
157.07900

[ PSA ]:
46.53000

[ LogP ]:
1.15000

[ Vapour Pressure ]:
0.00135mmHg at 25°C

[ Index of Refraction ]:
1.54

Phenoxyacetic acid-d5

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds