DEPMPO

Names

[ Name ]:
DEPMPO

[Synonym ]:
Phosphonic acid, (3,4-dihydro-2-methyl-1-oxido-2H-pyrrol-2-yl)-, diethyl ester
2-(diethoxyphosphoryl)-2-methyl-3,4-dihydro-2H-pyrrole 1-oxide
5-diethoxyphosphoryl-5-methyl-3,4-dihydro-5H-pyrrole N-oxide
Diethyl (2-methyl-1-oxido-3,4-dihydro-2H-pyrrol-2-yl)phosphonate
Phosphonic acid, P-(3,4-dihydro-2-methyl-1-oxido-2H-pyrrol-2-yl)-, diethyl ester
D3068
DEPMPO
5-(diethoxyphosphoryl)-5-methyl-1-pyrroline 1-oxide
5-(Diethylphosphono)-5-Methyl-1-pyrroline N-Oxide
5-diethoxyphosphoryl-5-methyl-4,5-dihydro-3H-pyrrole N-oxide
5-(diethoxyphosphoryl)-5-methyl-1-pyrrolidine N-oxide
5-(DIETHOXYPHOSPHORYL)-5-METHYL-1-PYRROLINE-N-OXIDE

Biological Activity

[Description]:

cDEPMPO is a potent anticancer prodrug. High concentrations of DEPMPO spin-trap the ·OH radical together with aryl radicals arising from one-electron reduced BTO (benzotriazine 1,4-di-N-oxide) compounds[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Qi W, et al. Spin Trapping Hydroxyl and Aryl Radicals of One-Electron Reduced Anticancer Benzotriazine 1,4-Dioxides. Molecules. 2022 Jan 26;27(3):812.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
412.4±34.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₁₈NO₄P

[ Molecular Weight ]:
235.22

[ Flash Point ]:
203.2±25.7 °C

[ Exact Mass ]:
235.097351

[ PSA ]:
74.09000

[ LogP ]:
-2.00

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.470

[ Storage condition ]:
-20°C

MSDS

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Safety Information

[ HS Code ]:
2933990090

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%