Procaspase-6 inhibitor 13
Names
[ CAS No. ]:
1575392-45-8
[ Name ]:
Procaspase-6 inhibitor 13
Biological Activity
[Description]:
Procaspase-6 inhibitor 13 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.38 uM.Procaspase-6 inhibitor 13 binds to pro-C6 at the dimer interface and contacts amino acids Y198, T199 and E214.Procaspase-6 inhibitor 13 significantly stabilizes procaspase-6.
[References]
1. Jeremy Murray, et al. ChemMedChem. 2014 Jan;9(1):73-7, 2.
Chemical & Physical Properties
[ Molecular Formula ]:
C16H14FN5O
[ Molecular Weight ]:
311.32