Diroximel fumarate

Names

[ Name ]:
Diroximel fumarate

[Synonym ]:
ALKS 8700
2-Butenedioic acid, 2-(2,5-dioxo-1-pyrrolidinyl)ethyl methyl ester, (2E)-
MFCD28502263
2-(2,5-Dioxo-1-pyrrolidinyl)ethyl methyl (2E)-2-butenedioate
Diroxamel fumarate
Diroximel fumarate
RDC-5108

Biological Activity

[Description]:

Diroximel fumarate (DRF) is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Angela Wehr, et al. Relative Bioavailability of Monomethyl Fumarate after Administration of ALKS 8700 and Dimethyl Fumarate in Healthy Subjects (P1.403). Neurology. Apr 2018.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
441.0±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₃NO₆

[ Molecular Weight ]:
255.224

[ Flash Point ]:
220.5±23.2 °C

[ Exact Mass ]:
255.074280

[ LogP ]:
-0.24

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.515

[ Storage condition ]:
-20℃

Diroximel fumarate

Names

Biological Activity

Chemical & Physical Properties

Related Compounds