Ac-IHIHIQI-NH2

Names

[ CAS No. ]:
1582727-85-2

[ Name ]:
Ac-IHIHIQI-NH2

Biological Activity

[Description]:

Ac-IHIHIQI-NH2 is a fibril-forming heptapeptide with high catalytic activity to laccase mimics. Ac-IHIHIQI-NH2 exhibits selectivity for hydrophobic p-nitrophenyl (ONp) ester substrates in the process of self-assembly[1][2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Ac-IHIHIQI-NH2 在 Zn2+ 存在下催化 p-nitrophenyl acetate (pNPA) 水解，在 pH 8 kcat/KM 值为 62 M-1s-1[2]。

[References]

[1]. Liu Q, et al. Supramolecular enzyme-mimicking catalysts self-assembled from peptides. iScience. 2022 Dec 20;26(1):105831.  

[2]. Heier JL, et al. Substrate specificity of an actively assembling amyloid catalyst. Biopolymers. 2017 Jan;108(1).  

Chemical & Physical Properties

[ Molecular Formula ]:
C43H71N13O9

[ Molecular Weight ]:
914.11

Related Compounds