Fmoc-Gly-NH-CH2-O-CH2-Cbz

Names

[ Name ]:
Fmoc-Gly-NH-CH2-O-CH2-Cbz

Biological Activity

[Description]:

Fmoc-Gly-NH-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-NH-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[References]

[1]. NOGUCHI, Shigeru, et al. Method for selectively manufacturing antibody-drug conjugate. WO2017002776A1.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
733.0±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₇H₂₆N₂O₆

[ Molecular Weight ]:
474.51

[ Flash Point ]:
397.1±32.9 °C

[ Exact Mass ]:
474.505

[ LogP ]:
4.97

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.600