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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

Names

[ CAS No. ]:
1599440-25-1

[ Name ]:
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

Biological Activity

[Description]:

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Masuda, Takeshi, et al. Conjugué anticorps-médicament. WO2014057687A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C28H36N6O10

[ Molecular Weight ]:
616.62

Related Compounds